One immediate rough edge I noticed when switching to #XFCE was that the "lock screen" feature didn't actually do anything out of the box. I was able to "fix" this by installing #Xscreensaver. I even found a cool screensaver that runs a #6502 emulator running various demos, but despite being set to go blank after 10 minutes it just keeps running.
It's a little wasteful of system resources, but I'm not even mad about it. It's like there's a mini rave in the office at night.